Scientific program
| Room/Hour | |
| 09:00 - 09:15 | Welcome |
| Session I Basic Mechanisms in Regulating Immune Responses Chaired by Siroon Bekkering (Netherlands) and Tania Crişan (Romania) |
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| 09:15 - 10:00 | Keynote Lecture Metabolic Pathways in Modulating Immunity Luke O’Neill (Ireland) |
| 10:00 - 10:30 | Invited speaker Towards effective host-directed therapy for tuberculosis Reinout van Crevel (Netherlands) |
| 10:30 - 10:45 | Invited speaker Genetic regulation of immune responses Anca Riza (Romania) |
| 10:45 - 11:00 | Selected oral from abstracts Itaconate and its derivatives induce long-term innate immune responses and confer protection against infections through trained immunity Anaisa Ferreira (Netherlands) |
| 11:00 - 11:30 | Break |
| 11:30 - 12:00 | Invited speaker Regulation of T-reg function Giuseppe Matarese (Italy) |
| 12:00 - 12:30 | Invited speaker Immunology of mRNA vaccines Botond Igyarto (USA) |
| 12:30 - 12:45 | Selected oral from abstracts Integrated single-cell analysis reveals adjuvant mediated epigenomic reprogramming of human bone marrow progenitors Yutaka Negishi (Netherlands) |
| 12:45 - 14:00 | Lunch |
| Session II Trained Immunity: The Innate Immune Memory of Host Defense Chaired by Jorge Domínguez-Andrés (Netherlands) and Anaísa Ferreira (Netherlands) |
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| 14:00 - 14:30 | Invited speaker Trained immunity as a treatment approach in cancer Triantafyllos Chavakis (Germany) |
| 14:30 - 15:00 | Invited speaker Innate immune mechanisms in tuberculosis Maziar Divangahi (Canada) |
| 15:00 - 15:15 | Selected oral from abstracts Training innate immunity in zebrafish using Shigella Margarida Gomes (United Kingdom) |
| 15:15 - 15:45 | Break |
| 15:45 - 16:00 | Invited speaker Cross-generational transmission of trained immunity Jorge Domínguez-Andrés (Netherlands) |
| 16:00 - 16:30 | Invited speaker Myeloid cell reprogramming in chronic inflammation George Hajishengallis (USA) |
| 16:30 - 17:00 | Invited speaker Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes Boris Novakovic (Australia) |
| 16:45 - 17:15 | Selected oral from abstracts Sex bias in trained immunity: a progesterone-based mechanism attenuates female secondary responses that can lead to decreased survival from infection Alexander Earhart (USA) |
| 17.15 - 19.00 | Poster session (I) |
| 19:00 | End of program day 1 On own for dinner Speakers Dinner |
| Room/Hour | |
| Session III Inflammation and Disease Chaired by Anna Aschenbrenner (Germany) and Boris Novakovic (Australia) |
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| 09:00 - 09:30 | Invited speaker Immunotherapy of severe infections Nikos Antonakos (Greece) |
| 09:30 - 09:45 | Invited speaker The role of inflammation in gout Tania Crisan (Romania) |
| 09:45 - 10:00 | Invited speaker Trained immunity in cardiovascular disease Siroon Bekkering (Netherlands) |
| 10:00 - 10:15 | Selected oral from abstracts Downregulation of genes of the type 1 interferon signaling pathway in uratetreated PBMCs and primary cells of hyperuricemic people Medeea Badi (Romania) |
| 10:15 - 10:45 | Break |
| 10:45 - 11:15 | Invited speaker Systems biology to understand diseases Yang Li (Germany) |
| 11:15 - 11:45 | Invited speaker Trained immunity in organ transplantation Raphael Duivenwoorden (Netherlands) |
| 11:45 - 12:00 | Selected oral from abstracts Kinase activity profiling in mevalonate kinase deficiency Frouwkje Politiek (Netherlands) |
| 12:00 - 12:15 | Selected oral from abstracts Innate immune cells´ cytokine production is regulated by epigenetic modifiers EHMT1, KMT2C and KMT2D Burcu Al (Germany) |
| 12:15 - 14:00 | Lunch and poster session (II) |
| Session IV INTERMEZZO Chaired by Maartje Jacobs-Cleophas (Germany) and Jessica dos Santos (Netherlands) |
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| 14:00 - 14:30 | Invited speaker How to publish a good paper Zoltan Fehervari (Senior editor, Nature – United Kingdom) |
| Session V Immune Dysregulation in HIV Infection Chaired by Maartje Jacobs-Cleophas (Germany) and Jessica dos Santos (Netherlands) |
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| 14:30 - 15:00 | Invited speaker The 2000 HIV study Andre van der Ven (Netherlands) |
| 15:00 - 15:15 | Selected oral from abstracts Blood immune cells of post-COVID-19 syndrome patients present with distinct alterations in their transcriptional states Charlotte Kröger (Germany) |
| 15:15 - 15:45 | Break |
| 15:45 - 16:15 | Invited speaker Single-cell sequencing immune cells in HIV Anna Aschenbrenner (Germany) |
| 16:15 - 16:30 | Selected oral from abstracts Plasma proteomics in patients living with HIV Nadira Vadaq (Netherlands) |
| 16:30 - 17:00 | Invited speaker The viral reservoir in HIV Linos Vandekerckhove (Belgium) |
| 17:00 | Closing and award ceremony |
| 19:00 | Conference dinner (Grand Hotel Napoca) |
| Room/Hour | Room 1 |
| 08:00 - 10:00 | Session I Chairs: Mihaela Lupse, Victoria Barlutiu |
| 08.00 - 08.20 | Analysis of COVID-19 vaccination in patients hospitalized to the Clinical Hospital for Infectious Diseases Cluj-Napoca during the fourth and fifth wave of the pandemic Violeta Briciu, Adriana Topan, Mihai Calin, Roxana Dobrota, Daniel Leucuta, Mihaela Lupse |
| 08.20 - 08.40 | Death risk factors in COVID-19 in the elderly Victoria Barlutiu |
| 08.40 - 09.00 | ICU experience in COVID-19 Lucia Herbel |
| 09.00 - 09.20 | Could vitamin D influence the evolution of COVID-19? Adriana Topan, Mihaela Lupse, Mihai Calin, Cristian Jianu, Daniel Leucuta, Violeta Briciu |
| 09.20 - 09.40 | Sepsis and COVID-19 Anca Georgescu |
| 09.40 - 10.00 | Clinical Characteristics and Outcomes of ICU vs. NON-ICU COVID-19 Patients Daniela Iancu |
| 10.00 - 10.20 | Coffee break |
| 10:20 - 13:00 | Session II Chairs: Simin Florescu, Anca Georgescu |
| 10.20 - 10.40 | The Oral Antiviral Solution for High Risk Patients with COVID-19 Mihaela Lupse |
| 10.40 - 11.00 | Antiviral therapy in COVID-19 Simin Florescu |
| 11.00 - 11.20 | Treatment with Tocilizumab in COVID-19 Amanda Radulescu |
| 11.20 - 11.40 | Treatment with Anakinra in COVID-19 Mihaela Lupse |
| 11.40 - 12.20 | The pandemic in ID and microbiology Brandusa Tilea, Edith Szekely |
| 12.20 - 12.50 | Updates for COVID-19 vaccination. New generation of pneumococcal vaccines for vulnerable patients Violeta Briciu |
| 12.50 - 13.00 | Discussions |
| 13.00 - 14.00 | Lunch |
| 14:00 - 16:00 | Session III Chairs: Dan Otelea, Violeta Briciu |
| 14.00 - 14.20 | CT evaluation of the patient with COVID-19, cancer screening Radiology Vasile Morar |
| 14.20 - 14.40 | Thrombotic complications in patients with COVID-19 Iulia Trif |
| 14.40 - 15.00 | Multiplex tests in the etiological diagnosis of infection Mirela Flonta |
| 15.00 - 15.20 | SARS-CoV2 and the evolution of molecular diagnostics Dan Otelea |
| 15.20 - 15.40 | Hepatic dysfunction in COVID-19 Monica Muntean |
| 15.40 - 16.00 | New biomarkers proposed in the diagnosis of sepsis Egidia Miftode |
| 16.00 - 16.20 | Coffee break |
| 16:20 - 18:00 | Session IV Chairs: Simona Rednic, Alina Elec |
| 16.20 - 16.40 | COVID-19 and autoimmune diseases Simona Rednic |
| 16.40 - 17.00 | Diabetes and COVID-19 Mihaela Gribovschi |
| 17.00 - 17.20 | COVID-19 in cancer patients Paul Kubelac |
| 17.20 - 17.40 | COVID-19 in patients with renal transplants Alina Elec |
| 17.40 - 18.00 | COVID-19 in the pediatric population with comorbidities Raluca Tripon, Vlad Barbos |
| 18.00 - 18.20 | COVID-19 and the pregnant woman Cristina Cismaru, Melinda Horvat |
| 18.20 - 18:30 | Conclusions. Closure |
| 20.00 | Dinner |
| Room/Hour | Room 2 |
| 08:20 - 10:00 | Session V Chairs: Mirela Flonta, Manuela Arbune |
| 08:20 - 08:40 | Antibiotic resistance in the pandemic Codrina Buta, Roxana Dobrota, Mirela Flonta |
| 08:40 - 09:00 | SINDROM POST-ICU, POST SEPSIS, POST COVID 19 Dumitru Cârstina |
| 09:00 - 09:20 | Long Covid. Adriana Hristea |
| 09:20 - 09:40 | MISC and MISA Manuela Arbune |
| 09:40 - 10:00 | Pulmonary damage in Long Covid at the patient with critical/severe form of COVID-19 Adela Teodorovici, Iulia Trifu, Alex Trifu, Vasile Morar, Ramona Boja, Violeta Briciu |
| 10.00 - 10.20 | Coffee break |
| 10:20 - 13:00 | Session VI Chairs: Corneliu Popescu, Dumitru Carstina |
| 10.20 - 10.40 | Monkey pox Corneliu Popescu |
| 10.40 - 11.00 | Coxiella Burnetti – Stealth Pathogen and Clinical Mimicker in Immunodepressed Patients Laura Damian |
| 11.00 - 11.20 | Emerging hemorrhagic fevers Mihai Rus |
| 11.20 - 11.40 | Toxoplasma Gondii In The Human Brain Could Modulate Local Immunity Against Cryptococcal Infection. Observation In Hiv-Positive Patients Ruxandra Moroti |
| 11.40 - 12.00 | Cardiovascular Risk Factors Correlated with Clinical Forms of Sars-Cov-2 Infection Brandusa Tilea |
| 12.00 - 12.20 | Prognostic Markers in Cancer Patients with COVID-19 Cristina Garbovan |
| 12.20 - 12.40 | Panel Based Molecular Diagnostics And Real Time Pcr Cycle Threshold (Ct) Values Mirela Flonta |
| 13.00 - 14.00 | Lunch |
| 14.00 - 16.00 | Rezi case - Session I Chairs: Simin Florescu, Dan Otelea, Amanda Radulescu, Monica Muntean, Cristina Cismaru |
| Coinfection Of Covid-19 And Seasonal Flu A And B. Clinical Case Report Ioana-Raluca Froicu, Ioana-Alexandra Dosinescu |
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| A Multi-Faced Aspect Of Clostridium Difficile Infection In Pediatric Patients With Inflammatory Bowel Disease – Case Presentation Elena Iana |
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| Viral Hepatitis A In Romanian Young Males Georgiana Neagu |
|
| Particularities Of Soft Tissue Infections With Multiple Localizations, Caused By Community Associated MRSA Alin Albu- Alika |
|
| Sporadic Prion Disease In A Patient With Paranoid Schizophrenia Lucian Flutur |
|
| A Case Of Haemophilus Influenzae Meningitis In The Context Of Chronic Bilateral Sphenoidal Sinusitis Bogdan Ghitoaica |
|
| Chickenpox-Associated Immune Thrombocytopenic Purpura In A 9-Year-Old Patient Vlad Alexandru Barbos |
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| Human Monkeypox And Syphilis Infections In A Newly Hiv-Diagnosed Patient: A Case Report Virginia Raboutet |
|
| 16.00 - 16.20 | Coffee break |
| 16:20 - 18:00 | Rezi case - Session II Chairs: Simin Florescu, Dan Otelea, Amanda Radulescu, Monica Muntean, Cristina Cismaru |
| Severe Plasmodium Falciparum Malaria, Severe Thrombocytopenia, Streptococcus Mitis Bacteremia, Persistent Atrial Fibrillation Converted To Sinus Rhythm Kinga - Maria Komlodi |
|
| A Case Of Listeria Monocytogenes Meningoencephalitis Complicated By Intracranial Haemorrhages And Hydrocephalus Crina Diaconu |
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| An Atypical Case Of Tuberculosis-Related Vasculitis Presenting With Arthralgia And Purpuric Lesions On The Lower Limbs Agnes Csiszer |
|
| Infective Endocarditis On Mechanical Prosthetic Aortic Valve With Multivisceral Complications Secondary To Septic Emboli In A Young, Drug-Using Patient With Multiple Comorbidities Cosmin - Daniel Jucan |
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| Persistent Detectable Sars-Cov-2 Viral Load In A Patient With Chronic Lymphocytic Leukemia Under Tratment With Anti-Cd20 Monoclonal Antibodies And Selective Bcl-2 Inhibitors Alexandru Sirbu |
|
| Endocardial Abscess With Community-Acquired Pseudomonas Aeruginosa In An Immunocompetent Patient Marius - Iulian Popovici |
|
| A Rare Case Of Endocarditis With Pantoea Agglomerans Daniela Iancu |
|
| Progressive Multifocal Leukoencephalopathy In An Apparent Immunocompetent Patient Paul - Stefan Panaitescu |
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| 18.20 - 18:30 | Conclusions. Closure |
| POSTER PRESENTATIONS | |
| PP01 | Glucose variability impacts long term immune alterations and hypoglycemia-induced inflammation in people with type 1 diabetes Mandala Ajie, Clementine Verhulst, Julia van Heck, Therese W Fabricius, Ulrik Pedersen-Bjergaard, Cees Tack, Rinke Stienstra, Bastiaan de Galan |
| PP02 | Improving trained immunity induced by BCG with b-glucan and Leishmania braziliensis: investigating the anti-tumor effects Aksu M.D., dos Santos J.C., Novakovic B., Joosten L.A.B., Netea M.G. |
| PP03 | A nature inspired platform for nucleic acid delivery to the myeloid cell compartment Tom Anbergen |
| PP04 | Sex-specific influence of visceral and subcutaneous adipose tissue volumes on systemic inflammation and innate immune activation in obese subjects Harsh Bahrar, Kiki Schraa, Inge C.L. van den Munckhof, Tessa Brand, Rob ter Horst, Marinette van der Graaf, Helena M. Dekker, Rinke Stienstra, Jacqueline de Graaf, Leo, A. B. Joosten, Mihai G. Netea, Niels. P. Riksen, Joost H.W. Rutten |
| PP05 | Investigating the modulation of metabolism to increase the efficacy of BCG vaccine Baydemir I., Floor E., Bulut O., Báez-Magaña M., Netea M.G., Domínguez-Andrés J. |
| PP06 | Plasma proteomics shows that MICA, IL1R1, FETUB and FOLR1 relate to HIV-1 reservoir M.J.T Blaauw, J. C. dos Santos1, N. Vadaq, W. Trypsteen, W. van der Heijden, L. Vandekerckhove, M. Netea, L. Joosten, A. van der Ven, V. Matzaraki |
| PP07 | A comprehensive genetic map of cytokine responses to pathogens in 1063 Lyme patients reveals novel regulatory mechanisms underlying diseases. Javier Botey-Bataller, Hedwig D. Vrijmoeth, Jeanine Ursinus, Bart-Jan Kullberg, Cees van den Wijngaard, Hadewych ter Hofstede, Cheng-Jian Xu, Mihai G. Netea, Joppe W.R. Hovius, Leo A.B. Joosten, Yang Li |
| PP08 | Understanding Host-Pathogen interactions of Mycobacterium tuberculosis-infected macrophages from patients with diabetes mellitus by using dual RNA-sequencing Julia Brake, Valerie Koeken, Jodie Schildkraut, Reinout van Crevel, Jakko van Ingen |
| PP09 | Myeloid cell reprogramming in calcific aortic valve stenosis Wieteke Broeders, Siroon Bekkering, Saloua El Messaoudi, Niels van Royen, Niels Riksen |
| PP10 | Recombinant Interferon Gamma restores altered immunometabolism in Chronic Granulomatous Disease Mariolina Bruno, Charlotte Kröger, Bowen Zhang, Anaísa Ferreira, Ruiqi Liu, Rutger Röring, Athanasios Ziogas, Laszlo Groh, Viola Klück, Simone Moorlag, Priya Debisarun, Nico Janssen, Diletta Rosati, Jorge Saiz, Orsi Gaal, Humberto Ferreira, Martina Uelft, Stefanie Herresthal, Matthias Becker, Lisa Holsten, Sophie Müller, Michael Kraut, Jonas Schulte-Schrepping, Lorenzo Bonaguro, Kristian Händler, Joachim Schultze, Cristina Cunha, Coral Barbas, Leo Joosten, Mihai Netea, Yang Li, Anna Aschenbrenner, Agostinho Carvalho, Frank van de Veerdonk |
| PP11 | Double-edged effects of resveratrol on trained immunity Ozlem Bulut, Ilayda Baydemir, Jorge Dominguez Andres, Mihai Netea |
| PP12 | Serum proteome profiles of gout and asymptomatic hyperuricemia reveal common and persistent inflammatory alterations Georgiana Cabau, Orsolya Gaal, Medeea Badii, Valentin Nica, Andreea-Manuela Mirea, Ioana Hotea, Cristina Pamfil, Simona Rednic, Radu A. Popp, Mihai G. Netea, Tania O. Crisan and Leo A.B. Joosten, |
| PP13 | Influence of Lenvatinib on the functional reprogramming of peripheral myeloid cells in patients with non-medullary thyroid carcinoma Peng Chungying |
| PP14 | Sex-specific association between adipose tissue inflammation and vascular and metabolic complications of obesity Benjamin Cossins, Inge van den Munckhof, Rinke Stienstra, Joost H.W. Rutten, Leo A.B. Joosten, Mihai G. Netea, Yang Li, Niels P. Riksen |
| PP15 | Traditional African diets modulate the immune status Godfrey Temba, Tal Pecht, Vesla Kullaya, Nadira Vadaq, Leo Joosten, Blandina Mmbaga, Andre van der Ven, Reginald Kavishe, Mihai Netea, Quirijn de Mast |
| PP16 | Complement activation in patients with sepsis: no relationship with inflammation or disease severity Aline H. de Nooijer, Antigone Kotsaki, Eleftheria Kranidioti, Matthijs Kox, Peter Pickkers, Erik J.M. Toonen, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea |
| PP17 | Different strategies to model neuroendocrine tumours using zebrafish and patient material Dona, M., Veltien A., van Raaij I., Olthaar A., Kusters B., van Herwaarden A.E., Scheenen T.W.J., Menke A., Heerschap A., Gorissen G., Timmers H.J.L.M. |
| PP18 | Host genetic variants regulates CCR5 expression on immune cells: a study in people living with HIV and healthy controls J.C. dos Santos, Z. Zhang, L.E. van Eekeren, E.T. Fok, N. Vadaq, L. van de Wijer, W.A. van der Heijden, V.A.C.M. Koeken, H.J. Koenen, M. Mhlanga, M.G. Netea, A.J. van der Ven, Y. Li |
| PP19 | BCG-LT: Long Term Assessment of Infectious Diseases and Immune Mediated Disorders after BCG (re)Vaccination Elisabeth Dulfer, Konstantin Föhse, Esther Taks, Josephine van de Maat, Mihai Netea |
| PP20 | Anti-IL-1Ra-autoantibodies in patients with severe COVID-19 and sepsis Job J. Engel, Caspar I. van der Made, Aline H. de Nooijer, Nikolaos Antonakos, Intan M.W. Dewi, Nico A.F.J. Janssen, Inge Grondman, Leo A.B. Joosten, Peter Pickkers, Matthijs Kox, Anton S.M. Dofferhoff, Marc J.T. Blaauw, Marjan J. van Apeldoorn, Erik J.M. Toonen, Mihai G. Netea, Evangelos J. Giamarellos-Bourboulis, Frank L. van de Veerdonk |
| PP21 | Leptin, Inflammation and trained immunity in obesity Daniela Flores Gomez, Siroon Bekkering, Benjamin Cossins, Rob ter Horst, Vasiliki Matzaraki, Mihai G Netea, Niels P Riksen |
| PP22 | Gout-associated SNP at the IL1RN-IL1F10 region is functionally linked to altered cytokine production in PBMCs of patients with gout and controls Orsolya I. Gaal, Medeea Badii, Megan Leask, Valentin Nica, HINT Consortium, Tania O. Crișan, Tony R. Merriman, Leo A.B. Joosten |
| PP23 | Differential anti-viral responses in individuals of Indian and Dutch origin: relevance for the COVID-19 pandemic Büşranur Geckin |
| PP24 | Lipidomic Analysis of 300-OB; Identification of contradictions amongst cohort, accordant with Cardiovascular and Metabolic markers Arslan Hamid |
| PP25 | Innate and adaptive immune interactions in trained immunity: T cell activation and differentiation Leonie Helder, Laszlo Groh, Anaisa Valido, Mihai Netea, Leo Joosten, Gert Jan Scheffer |
| PP26 | Exploring the potential of SIGLEC15 as novel immunotherapeutic agent in (thyroid) cancer: focus on innate immune cells M. Jaeger, L. van Emst, M. Netea , L.A.B. Joosten, R. Netea-Maier |
| PP27 | Increased cytokine production in patients with left ventricular diastolic dysfunction and heart failure with preserved ejection fraction – a role for trained immunity? Elise L. Kessler, Daniek Kapteijn, Marleen C. Glade, Siroon Bekkering, Hester M. den Ruijter, Saskia C.A. de Jager, Niels P. Riksen |
| PP28 | RORα is a regulator of BCG-induced trained immunity Gizem Kilic, Simone JCFM Moorlag, Rob ter Horst, Valerie ACM Koeken, L Charlotte J de Bree, Vera P Mourits, Leo AB Joosten, Jorge Domínguez-Andrés, Mihai G Netea |
| PP29 | Application of multi-epigenomic techniques to human fetal and adult endothelial cells to study Trained Immunity Bowon Kim, Elisa Weiss, Rebecca Shepherd, Sachintha Wijegunasekara, Dhanya Shanmuganathan, Thomas Aitken, Richard Saffery, Ursula Hiden, Boris Novakovic |
| PP30 | Effects of discontinuing urate-lowering therapy in gouty arthritis: a Cohort Study Brenda Kischkel, Chon-Kit Chou, Iris Rose Peeters, Noortje van Herwaarden, Tania O. Crisan, Alfons den Broeder, Leo A. B. Joosten |
| PP31 | Single-cell omics to decipher Dexamethasone action in COVID-19: a clinical phase-II study Rainer Knoll, Sophie Müller, Martina van Uelft, Lorenzo Bonaguro, Elisa Helbig, Joachim L. Schultze, Florian Kurth, Anna C. Aschenbrenner |
| PP32 | Hyperinflammation in tuberculosis Lisa Kurver, Valerie Koeken, Reinout van Crevel, Gabriele Pollara, Arjan van Laarhoven |
| PP33 | An exploratory study to identify the mechanisms of autoinflammatory processes present in Hyperimmunoglobulin D syndrome (HIDS) Ruiqi Liu, Rutger J. Röring, Bowen Zhang, Anna Aschenbrenner, Simone J.C.F.M. Moorlag, Mariolina Bruno, Viola Klück, Laszlo Groh, Priya Debisarun, Orsi Gaal, Medea Badii, Joachim L. Schultze, Yang Li, Chengjian Xu, Frank L. van de Veerdonk, Leo A.B. Joosten, Mihai G. Netea |
| PP34 | SARS-CoV-2 Humoral Immunity in a Cohort of Patients with Head and Neck Carcinoma Luminița Măruțescu, Alexandru Enea, Elena Dragu, Marcela Popa, Diana Antonia Costea, Marian Neculae, Carmen Chifiriuc, Elena Codrici, Violeta Ristoiu, Veronica Lazăr, Raluca Grigore, Petronela Ancuța |
| PP35 | Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Gout and Hyperuricemic patients Valentin Nica, Georgiana Cabău, Orsolya Gaal, Medeea Badii, Andreea-Manuela Mirea, Ioana Hotea, Cristina Pamfil, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A.B. Joosten |
| PP36 | Identification of sepsis endotypes and biomarkers using circulatory proteins Isis Ricaño-Ponce, Eleftheria Kranidioti, Inge Grondman, Nikolaos Antonakos, Aline H. de Nooijer, Vinod Kumar, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea |
| PP37 | Modulation of the vaginal microbiota impacts innate immune response D. Rosati, M. Valentine, M. Bruno, B. Hube, M. Gresnigt, M. Netea |
| PP38 | Inducing trained immunity with interleukin-4 nanotherapy to overcome immunoparalysis Schrijver D., Röring R., Deckers J., de Dreu A., Toner Y., Prevot G., Priem B., Munitz J., Nugraha E., van Elsas, Y., Azzun A., Anbergen T., Groh L., Becker A., Pérez-Medina C., Oosterwijk R., Novakovic B., Moorlag S., Jansen A., Pickkers P., Kox M., Beldman T., Kluza E., van Leent M., Teunissen A., van der Meel R., Fayad Z., Joosten L.,7, Fisher E., Merkx M., Netea M., Mulder M. |
| PP39 | Targeting glutaminolysis pathway in trained immunity induced by oxLDL Alice Scarpa, Laszlo Groh, Siroon Bekkering, Katarzyna Placek, Mihai Netea, Niels Riksen |
| PP40 | Assessment of the pyrin inflammasome pathway in urate-induced inflammation Ancuta R. Straton, Medeea Badii, Georgiana Cabău, Orsolya Gaal, Valentin Nica, HINT Consortium, Cristina Pamfil, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten |
| PP41 | Efficacy of bacillus Calmette-Guérin vaccination against respiratory tract infections in the elderly during the COVID-19 pandemic Esther J.M. Taks, Simone J.C.F.M. Moorlag, Thijs ten Doesschate, Thomas van der Vaart, Axel Janssen, Lisa Müller, Philipp Ostermann, Helga Dijkstra, Heidi Lemmers, Elles Simonetti, Marc Mazur, Heiner Schaal, Rob ter Heine, Frank L. van de Veerdonk, Chantal P. Bleeker-Rovers, Reinout van Crevel, Jaap ten Oever, Marien I. de Jonge, Marc J. Bonten, Cornelis H. van Werkhoven, Mihai G. Netea |
| PP42 | Clonal Hematopoiesis and Inflammation in Obesity Helin Tercan, Benjamin Cossins, Rosanne van Deuren, Kiki Schraa, Rob ter Horst, Inge CL van den Munckhof, Siroon Bekkering, Joost Rutten, Mihai G Netea, Leo AB Joosten, Alexander Hoischen, Niels P Riksen |
| PP43 | IL-38 inhibits the induction of trained immunity in human macrophages Lisa Teufel, Dennis M. De Graaf, Vasiliki Matzaraki, Leo A. B. Joosten, Mihai G. Netea |
| PP44 | Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer Yohana Toner |
| PP45 | Impact of pathogen-induced inflammation on the function and metabolic status of effector CD8 T cells Bram Van Den Eeckhout, Jozefien De Clercq, Charlotte Grootaert, Marlies Ballegeer, Elianne Burg, Liesbeth Couck, Loïc Schrooyen, Jolien Van Cleemput, Wim Van Den Broeck, Andreja Rajkovic, Xavier Saelens, Linos Vandekerckhove, Sarah Gerlo |
| PP46 | Hypermorphic heterozygous variants in the tyrosine kinase ZAP-70 underlie autoimmune disease Caspar I. van der Made, Ruben L. Smeets, J. Potjewijd, Annet Simons, Emil E. Vorsteveld, Janneke H.M. Schuurs-Hoeijmakers, Sonja A. de Munnik, M. Vreeburg, Hans J.P.M. Koenen, Mihai G. Netea, Gijs T.J. van Well, Frank L. van de Veerdonk, Alexander Hoischen |
| PP47 | Sustained pro-inflammatory effects following hypoglycaemia in people with type 1 or type 2 diabetes Julia IP van Heck, Clementine EM Verhulst, Therese W Fabricius, Rinke Stienstra, Cees J Tack, Ulrik Pedersen-Bjergaard, Bastiaan E de Galan |
| PP48 | Reprogramming progenitor immune cells in non-medullary thyroid carcinoma using trained immunity. Pepijn van Houten, Martin Jaeger, Katrin Rabold, Willem Mulder, Johannes de Wildt, Willemijn Hobo, Manita Bremmers, Ilse van Engen-van Grunsven, Mihai Netea, Romana Netea-Maier |
| PP49 | Interleukin-1 receptor antagonist anakinra as treatment for paradoxical responses in HIV-negative tuberculosis patients: a case series Cynthia van Arkel, Martin Boeree, Cécile Magis-Escurra, Wouter Hoefsloot, Neeltje Carpaij, Jakko van Ingen, Sjoert Pegge, Pascal Wielders, Frank Smeenk, Rob Aarnoutse, Mihai G. Netea, Reinout van Crevel, Arjan van Laarhoven |
| PP50 | Single cell multi-omic insights into PBMC induced by P. aeruginosa Liang Zhou, Saumya D Kumar, Ahmed Alaswad, Martijn Zoodsma, Valerie A.C.M. Koeken, Cheng-Jian Xu, Suzanne Haussler, Yang Li |
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